From 1935 to 1962, Luise worked with her husband as an active partner in their Hanson Furniture Store and Funeral Home. She was integral in the founding of Winnebago Industries in 1959 and Stitchcraft, which soon followed. She worked as an interior designer before being elected director and treasurer in 1965, then director and vice president in 1967. She was named director emeritus in 1981. Luise also served on the board of directors of Manufacturers Bank and Trust in Forest City.